SWAN Publications
Loss of mitochondrial DNA helicase in retinal macroglia drives neovascular retinopathy
Olander S, Karaman S, Suomi F, Aguilar K, Zhaivoron A, Nedergaard M, Smeds L, Tiihonen J, Quintana A, Hidalgo J, Alitalo K, Ala-Laurila P, Ince-Dunn G, Suomalainen A
EMBO Molecular Medicine 2026
Food sources of macro- and micronutrients in young children and adults following vegan, vegetarian, and omnivorous diets
Tilli V, Hovinen T, Kettunen E, Freese R, Itkonen ST, Erkkola M, Suomalainen A, Korkalo L
European Journal of Nutrition 2026, 65: 88
Bone and mineral metabolism in 2-7-year-old Finnish children and their caregivers following vegan, vegetarian, and omnivorous diets
Itkonen ST, Hovinen T, Kettunen E, Freese R, Tilli V, Cashman KD, Erkkola M, Suomalainen A, Korkalo L
European Journal of Nutrition 2026, 64: 276
Metabolic costs and trade-offs of hypermetabolism in human motor neurons with ATP synthase deficiency
Torregrosa-Muñumer R, Turkia J, Ermiş R, Kvist J, Harjuhaahto S, Pennonen J, Hietakangas V, Ylikallio E, Tyynismaa H
Communications Biology 2025, 8: 1759
Genome-wide association analyses of autoimmune hypothyroidism reveal autoimmune and thyroid-specific contributions and an inverse relationship with cancer risk
Reeve MP, Kanai M, Graham DB, Karjalainen J, Luo S, Kolosov N, Adams C; Ritari J, Karczewski KJ, Kiiskinen T, Jiang Y, Fuller Z, Mehtonen J, Kurki MI, Khan Z, FinnGen, Partanen J, McCarthy MI, Artomov M, Palotie A, Tuomi T, Pirinen M, Kero J, Xavier RJ, Daly MJ, Ripatti S
Nature Genetics 2026, 58: 550-559
Limited overlap between genetic effects on disease susceptibility and disease survival
Yang Z, Pajuste FD, Zguro K, Cheng Y, Kurant DE, Eoli A, Wanner J, Jermy B, Rämö J, FinnGen, Kanoni S, van Heel DA, Genes & Health Research Team, Hayward C, Marioni RE, McCartney DL, Renieri A, Furini S, INTERVENE consortium, Mägi R, Gusev A, Drineas P, Paschou P, Heyne H, Ripatti S, Mars N, Ganna A
Nature Genetics 2025, 57: 2418-2426
Cross-biobank generalizability and accuracy of electronic health record-based predictors compared to polygenic scores
Detrois KE, Hartonen T, Teder-Laving M, Jermy B, Läll K, Yang Z, Estonian Biobank research team, FinnGen, Mägi R, Ripatti S, Ganna A
Nature genetics 2025, 57: 2136-2145
Linking variability of leukocyte lipid metabolism to circulating lipids, lipoprotein composition, and cardiovascular risk in the Finnish adult population
Hlushchenko I, Pamilo S, Islam MM, Lähdeniemi IAK, Tamlander M, Ripatti S, Pfisterer SG
Arteriosclerosis, Thrombosis, and Vascular Biology 2025, 45: 1416-1431
Autophagy-regulated mitochondrial inheritance controls early CD8(+) T cell fate commitment
Borsa M, Lechuga-Vieco AV, Kayvanjoo AH, Jenkins E, Yazicioglu Y, Compeer EB, Richter FC, Rapp S, Mitchell R, Youdale T, Bui H, Kuuluvainen E, Dustin ML, Sinclair LV, Katajisto P, Simon AK
Nature Cell Biology 2026, 28: 66-81
Stem-cell-derived beta cells mature metabolically upon murine engraftment
Vähäkangas E, Saarimäki-Vire J, Montaser H, Lithovius V, Eurola S, Ibrahim H, Kuuluvainen E, Balboa D, Katajisto P, Barsby T, Otonkoski T
Diabetologia 2025, 68: 1997-2010
Human whole-blood NAD(+) levels do not vary with age or lifestyle interventions
Trętowicz MM, Scantlebery AML, Schomakers BV, Eroğlu KD, van Weeghel M, Spek V, Vinten KT; Legon L, Coskun E, Millan-Domingo F, Olaso-Gonzalez G, Gomez-Cabrera MC, Montoro-García S, Noguera-Navarro C, van Kuilenburg ABP, Moco S, van Hattum JC, Jørstad HT, Benali M, van der Helder J, Biersteker EJM, Muniandy M, Pietiläinen KH, Pirinen E, Slagboom PE, Beekman M, Deelen J, Zapata-Pérez R, Weijs PJM, Tieland M, Janssens GE, Houtkooper RH
Nature Metabolism 2026
Opposing patterns in eating behaviors following bariatric surgery versus lifestyle-induced weight loss
Vuorela L, Berntzen BJ, Muniandy M, Saarinen T, Meriläinen S, Koivukangas V, Suojanen L, Groop PH, Rissanen A, Virtanen K, Juuti A, Pietiläinen KH, Heinonen S
PloS One 2026, 21: e0346240
Adipose single cell epigenome and transcriptome localize genetic risk for cardiometabolic disease and accelerated aging
Lee SHT, Kar A, Gelev KZ, Chen ZJ, Das SS, Heinonen S, Saarinen T, Vaittinen M, Kaminska D, Peltoniemi H, Luo C, Juuti A, Männistö V, Pihlajamäki J, Kaikkonen MU, Pietiläinen KH, Balliu B, Pajukanta P
Nature communications 2026
Human Skeletal Muscle Mitochondria Responses to Weight Loss Induced by Bariatric Surgery or Lifestyle Intervention
van der Kolk BW, Heinonen S, White JW, Wagner A, Karppinen JE, Saari S, Muniandy M; Metsikkö S, Dillon ET, Groop PH, Saarinen T, Le Roux CW, Virtanen KA, Docherty NG, Pirinen E, Juuti A, Pietiläinen KH
Acta Physiologica (Oxford, England) 2026, 242: e70150
Greater early postprandial GLP-1 increase after Roux-en-Y than one-anastomosis gastric bypass, with unchanged secretin: a randomized controlled trial
Heinonen S, Karppinen JE, Saarinen T, Groop PH, Juuti A, Holst JJ, Pietiläinen KH
International Journal of Obesity 2026
The effect of obesity and aging on NAD(+)/Sirtuin metabolism transcription and DNA methylation in subcutaneous adipose tissue of monozygotic twin pairs discordant for BMI
Lapatto HAK, van der Kolk BW, Muniandy M, Heinonen S, Heikkinen A, Alvarez M, Lee SHT, Jokinen R, Lundbom J, Kuula J, Hakkarainen A, Groop PH, Kaprio J, Tukiainen T, Ollikainen M, Pajukanta P, Pirinen E, Pietiläinen KH
International Journal of Obesity 2026, 50: 797-805
Distinct fasting and postprandial bile acid responses following Roux-en-Y and one-anastomosis gastric bypass
Jänis M, Saarinen T, Karppinen JE, Groop PH, Neuvonen M, Niemi M, Juuti A, Pietiläinen KH, Heinonen S
International Journal of Obesity 2026
Sex-specific Subcutaneous adipose tissue transcriptome in obesity: Insights from monozygotic twin pairs discordant for BMI
Haltia H, Muniandy M, Heinonen S, Saari S, Alvarez M, Hakkarainen A, Lundbom J, Kuula J, Groop PH, Kaprio J, Pajukanta P, Pietiläinen KH, van der Kolk BW
Obesity 2026, 34: 394-406
Blood and adipose tissue DNA methylation in adults born preterm with a very low birth weight - a sibling comparison study
Hauta-Alus HH, Ronkainen J, Kuula J, Czamara D, Heiskala A, Sandboge S, Björkqvist J, Kaseva N, Räikkönen K, Pietiläinen KH, Sebert S, Kajantie E
Epigenomics 2026, 18: 1-14
Computational modeling enables individual assessment of postprandial glucose and insulin responses after bariatric surgery
Poyraz O, Heinonen S, John ST, Saarinen T, Juuti A, Marttinen P, Pietiläinen KH
Communications Medicine 2025, 5: 434
Single-cell DNA methylome and 3D genome atlas of human subcutaneous adipose tissue
Chen ZJ, Das SS, Kar A, Lee SHT, Abuhanna KD, Alvarez M, Sukhatme MG, Wang Z, Gelev KZ, Heffel MG, Zhang Y, Avram O, Rahmani E, Sankararaman S, Laakso M, Heinonen S, Peltoniemi H, Halperin E, Pietiläinen KH, Luo C, Pajukanta P
Nature Genetics 2025. 57: 2238-2249
Adipogenin promotes the development of lipid droplets by binding a dodecameric seipin complex
Li C, Sun XN, Funcke JB, Vanharanta L, Prasanna X, Gov K, Li Y, Virostek M, Joung C, Joffin N, Kanerva K, Szkalisity A, Kulig W, Straub L, Chen S, Velasco J, Cobb A, La Padula D, Wang MY, Onodera T, Vörös C, Kim DS, Kim M, Varlamov O, Li Y, Liu C, Nawrocki AR, Zhao S, Oh DY, Wang ZV, Gordillo R, Goodman JM, Wynn RM, Henne WM, Vattulainen I, Han Y, Ikonen E, Scherer PE
Science 2025, 390: eadr9755
Otsikko
Kirjoittajat
Lehti
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Otsikko
Kirjoittajat
Lehti
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Otsikko
Kirjoittajat
Lehti
Link to the publication
Otsikko
Kirjoittajat
Lehti
Link to the publication